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Symptoms of Amyloidosis

If you experience one or more of these, contact your doctor.

  • Symptoms for all forms of amyloidosis
    • Fatigue
    • Weight loss
    • Enlarged liver
    • Enlarged spleen
    • Signs of heart failure
The extent of the disease and the type of organ affected determine the symptoms if any. They can vary from mild to severe. The following is a list of additional symptoms as they relate to specific body systems:

  • Urinary tract
  • Skin
    • Easy bruising
    • Skin purpura (purplish skin around the eyes caused by small blood vessels leaking into the skin)
  • Lymphatic system
    • Enlarged lymph nodes
  • Endocrine system
    • Enlarged thyroid gland
  • Digestive System
    • Swallowing difficulties
    • Enlarged tongue
    • Enlarged liver
    • Diarrhea
    • Intestinal obstruction
    • Malabsorption (inadequate absorption of nutrients from the intestinal tract)
    • Clay colored stools
  • Neurologic system
    • Dementia -possible link to development of Alzheimer’s disease
    • Numbness, tingling, weakness in hands and feet
    • Swelling of nerves in the wrist
    • Weak hand grip
  • Cardiovascular system
    • Fluid accumulation in the tissues, causing swelling (edema)
    • Abnormal heart rhythm (arrhythmia)
    • Enlarged heart
    • Heart failure
    • Sudden death
    • Respiratory system
    • Difficulty breathing
    • Shortness of breath

Edema in Lower Legs

Amyloidosis

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